Inhibition of Gonadotropin and Prostaglandin Stimulation of Testicular Steroidogenesis in Malnourished Rats
- 24 April 2009
- journal article
- research article
- Published by Hindawi Limited in Andrologia
- Vol. 16 (5) , 406-409
- https://doi.org/10.1111/j.1439-0272.1984.tb00383.x
Abstract
The effect of human chorionic gonadotropin (hCG) and prostaglandin E1 (PGE1) on testicular steroidogenesis in protein-deficient and refed rats was studied in vitro. The malnourished, refed and control rats were found to secret testosterone in response to hCG and PGE1 stimulation. There was a significant reduction in the basal level of secretion in the malnourished rat testis (1.0 .+-. 0.4 nmol/3 h/testis). Malnourished rats refed with adequate protein diet responded to hCG and PGE1 stimulation in a similar manner to normally-fed adult rats.Keywords
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