Respiratory impedance and derived parameters in young children by forced random noise

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Abstract
The frequency dependence of total respiratory impedance during spontaneous breathing was measured repeatedly in 16 children (3-5 yr old) over 3 mo. using forced random noise and spectral analysis. Total respiratory resistance, compliance and inertance, which were calculated from the impedance data using regression analysis with a 2nd order model, had overall mean values .+-. SD of 5.61 .+-. 0.49 cmH2O.cntdot.1-1.cntdot.s, 4.03 .+-. 1.04 ml.cntdot.cmH2O-1 and 0.0120 .+-. 0.0024 cmH2O.cntdot.1-1.cntdot.s2, respectively. Linear regression analysis showed that resistance and compliance correlated with either height or forced vital capacity with r [correlation coefficient] values of 0.77-0.89. Analysis of measurement variability suggested that resistance measurements had, on the average, a coefficient of variation of 15%; corresponding values for compliance and inertance measurements were 25%.