What Does the Cryotherapy Preliminary Report Mean?
- 1 June 1988
- journal article
- clinical trial
- Published by American Academy of Pediatrics (AAP) in Pediatrics
- Vol. 81 (6) , 884-886
- https://doi.org/10.1542/peds.81.6.884
Abstract
The dispassionate numbers in the preliminary report of the Multicenter Trial of Cryotherapy for Retinopathy of Prematurity (CRYO-ROP)1 fail to convey the excitement I feel as a physician who now, for the first time, has a tested intervention to offer the infant with serious retinopathy of prematurity. Infants with retinopathy of prematurity at the study's threshold of severity have a 43% incidence of an unfavorable outcome in that eye, eg, retinal detachment or a fold across the macula. Either of these outcomes means severely reduced vision for life. Cryotherapy reduces the chances of an unfavorable outcome to 22%. The preliminary report, however, has left many questions unanswered.Keywords
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