Dynamic properties of the first steps of enzymatic reaction of porcine pancreatic elastase (PPE). 2. Molecular dynamics simulation of a Michaelis complex: PPE and hexapeptide Thr-Pro-n-Val-Leu-Tyr-Thr

This publication has 17 references indexed in Scilit:

• Theoretical correlation of structure and energetics in the catalytic reaction of trypsin
  Journal of the American Chemical Society, 1986
• Toward computer-aided site-directed mutagenesis of enzymes.
  Proceedings of the National Academy of Sciences, 1986
• The nature of enzyme catalysis in trypsin.
  Proceedings of the National Academy of Sciences, 1986
• Direct determination of the protonation states of aspartic acid-102 and histidine-57 in the tetrahedral intermediate of the serine proteases: neutron structure of trypsin
  Biochemistry, 1981
• Theoretical calculations on proton-transfer energetics: studies of methanol, imidazole, formic acid, and methaneethiol as models for the serine and cysteine proteases
  Journal of the American Chemical Society, 1981
• Stereochemical aspects of peptide hydrolysis catalyzed by serine proteases of the chymotrypsin type
  Bioorganic Chemistry, 1981
• Nitrogen-15 nuclear magnetic resonance spectroscopy. The state of histidine in the catalytic triad of .alpha.-lytic protease. Implications for the charge-relay mechanism of peptide-bond cleavage by serine proteases
  Journal of the American Chemical Society, 1978
• Zymogen activation in serine proteinases. Proton magnetic resonance pH titration studies of the two histidines of bovine chymotrypsinogen A and chymotrypsin A.alpha.
  Biochemistry, 1978
• The pH dependence of tritium exchange with the C-2 protons of the histidines in bovine trypsin
  Biochemistry, 1976
• Three-dimensional Structure of Tosyl-α-chymotrypsin
  Nature, 1967