Analgesic Use and Renal Function in Men

Open Access
Publisher Website
Google Scholar
Abstract
Nonnarcotic analgesics are among the most widely used medications and are used at least weekly by one quarter of US adults.1-3 High acute doses of analgesics, particularly nonsteroidal anti-inflammatory drugs (NSAIDs), have been implicated as causes of acute renal failure,4-7 which is most commonly seen among patients with impaired renal function. It has also been suggested that prolonged use of various analgesics may cause progressive renal damage ultimately leading to chronic kidney failure. The earliest study linking chronic analgesic use and chronic renal dysfunction was reported almost 50 years ago.8 In the ensuing half century, numerous case reports, several case-control studies, and 2 small cohort studies have raised the possibility of an association between use of various analgesics and chronic renal disease.

This publication has 2 references indexed in Scilit: