Adenocarcinoma of the extrahepatic bile duct in a cat

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Abstract
A scirrhous adenocarcinoma of the extrahepatic bile duct was shown by histopathological examination to be the cause of obstructive jaundice in an 11‐year‐old female Siamese cat. In addition to icterus, the cat's clinical signs included depression, anorexia, vomiting, constipation, weight loss and dehydration. Symptomatic therapy relieved the anorexia, constipation, dehydration and depression, but jaundice, weight loss and occasional vomiting continued during the 2‐month course of illness. Serum cholesterol and serum glutamic pyruvic transaminase (SGPT) remained elevated and serum bilirubin and serum alkaline phosphatase (SAP) values progressively increased from the cat's initial presentation to its death 2 months later. At necropsy the tumour was found to involve only the extrahepatic bile duct. Neoplasia of the extrahepatic biliary system has been reported only twice in domesticated animals (Patnaik et al., 1975; Feldman, Strafuss & Gabbert, 1976).