Marcescin, an Antibiotic Substance from Serratia marcescens
- 1 September 1950
- journal article
- research article
- Published by Microbiology Society in Journal of General Microbiology
- Vol. 4 (3) , 417-433
- https://doi.org/10.1099/00221287-4-3-417
Abstract
This thermostable polypeptide inhibits growth of Corynebacterium diphtheriae at 0.01 mg./ml. and Staphlococcus aureus at 0.1 mg./ml. It is very toxic to mice and sublethal doses did not protect against sensitive organisms. Yield is good from an aerated ammonium citrate-glycerol medium at 24[degree]. The antibiotic is probably different from some others obtained by similar processes. It is adsorbed by bacteria at a very high rate and it is therefore not possible to distinguish bacteriostatic from bactericidal properties.Keywords
This publication has 1 reference indexed in Scilit:
- THE FERMENTATION OF GLUCOSE BY ORGANISMS OF THE GENUS SERRATIAJournal of Bacteriology, 1928