Enantiospecific synthesis of (6R, 7S)-diastereoisomer of asperlin
- 1 July 1990
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Chemistry
- Vol. 68 (7) , 1035-1037
- https://doi.org/10.1139/v90-161
Abstract
An unambiguous synthesis of the (6R,7S)-diastereoisomer of asperlin from D-glucose involving a tandem epoxide formation/intramolecular Wadsworth–Emmons–Horner olefination has established the absolute configuration of the oxirane moiety in natural asperlin as (6S,7R). Keywords: asperlin, synthesis; Wadsworth–Emmons–Horner olefination; epoxide formation.This publication has 2 references indexed in Scilit:
- The synthesis of D-asperlinCanadian Journal of Chemistry, 1987
- Synthesis and stereochemistry of 2-pyrone derivatives related to some fungal metabolitesCanadian Journal of Chemistry, 1978