Preparation of Functionalized α-Chloromethyl Ketones Using Rieke Zinc
- 1 December 1995
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 25 (23) , 3923-3930
- https://doi.org/10.1080/00397919508011467
Abstract
The cross-coupling reaction of highly functionalized organozinc reagents with chloroacetyl chloride mediated by copper allows for the easy preparation of functonalized α-chloromethyl ketones in excellent yields.Keywords
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