Antioxidant potential of intermediates in phenylpropanoid metabolism in higher plants
- 10 July 1995
- journal article
- Published by Wiley in FEBS Letters
- Vol. 368 (1) , 188-192
- https://doi.org/10.1016/0014-5793(95)00639-q
Abstract
In this study the antioxidant activities of the hydroxycinnamic acids, chlorogenic, caffeic, ferulic and p-coumaric have been investigated in peroxidising lipid systems mediated by metmyoglobin. The results show that the order of effectiveness in increasing the resistance of LDL to peroxidation, in protecting LDL cholesterol from oxidation and preventing the oxidative modification of the LDL apoprotein B100 is caffeic = chlorogenic > ferulic > p-coumaric acid. Assessment of the rates of reaction of the hydroxycinnamates with ferrylmyoglobin, a product of the reductive decomposition of lipid hydroperoxides, reveals that the compounds are more effective as peroxyl radical scavengers than reductants of ferryl myoglobin in peroxidising LDL systems mediated by haem proteins.Keywords
This publication has 41 references indexed in Scilit:
- Asthma controlThe Lancet, 1994
- Caffeic acid phenethyl ester as a lipoxygenase inhibitor with antioxidant propertiesFEBS Letters, 1993
- Oxidised low density lipoproteins induce iron release from activated myoglobinFEBS Letters, 1993
- Content of potentially anticarcinogenic flavonoids of 28 vegetables and 9 fruits commonly consumed in the NetherlandsJournal of Agricultural and Food Chemistry, 1992
- Fruit, vegetables, and cancer prevention: A review of the epidemiological evidenceNutrition and Cancer, 1992
- The modulation of ferryl myoglobin formation and its oxidative effects on low density lipoproteins by nitric oxideFEBS Letters, 1991
- Ultraviolet-treated lipoproteins as a model system for the study of the biological effects of lipid peroxides on cultured cells. III. The protective effect of antioxidants (probucol, catechin, vitamin E) against the cytotoxicity of oxidized LDL occurs in two different waysBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1991
- Antioxidants/antimutagens in foodCritical Reviews in Food Science and Nutrition, 1990
- Linear furocoumarin accumulation in celery plants infected with erwinia carotovora pv. carotovoraJournal of Agricultural and Food Chemistry, 1987
- Antioxidant activity of flavonoids and reactivity with peroxy radicalPhytochemistry, 1986