Incorporating Toxicity Considerations Into the Design of Two-Stage Phase II Clinical Trials

1 December 1995

journal article
Published by JSTOR

Vol. 51 (4) , 1372-83
https://doi.org/10.2307/2533268

Abstract

Phase II study designs are proposed that evaluate both clinical response and toxicity, and that are similar in structure to Simon's two-stage designs. Sampl...

Keywords

TREATMENT
STRUCTURES
PHASE II
TWO STAGE
CLINICAL RESPONSE
ERROR RATES
RESPONSE AND TOXICITY

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