The Clinical Significance ofCitrobacter intermedium

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Abstract
Citrobacter intermedium was cultured from 52 human specimens. This organism was evaluated by means of its biochemical and clinical significance. C. intermedium was always found to reduce nitrates, utilize citrate, and ferment rhamnose, glucose, maltose, and lactose. Hydrogen sulfide production was not evident. These bacteria were frequently associated with neoplastic disease, cellulitis, septicemia, and urinary tract infections. The strains tested were sensitive to chloramphenicol, nalidixic acid, neomycin, kanamycin, and polymyxin B. Resistance was observed for nafcillin. Sensitivity to penicillin was erratic. The role of diminished host resistance appears to be a significant factor in establishing C. intermedium as a pathogen.

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