THE ASCHHEIM-ZONDEK HORMONE TEST FOR PREGNANCY

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Abstract
The desirability of a dependable laboratory test for the diagnosis of pregnancy has been recognized for a long time. The Abderhalden serum reaction, although giving great promise at first, has been abandoned on account of its unreliability. Other procedures, such as the epinephrine test, are likewise of slight value. In recent years, the isolation of the ovarian hormone and the discovery of the influence of the anterior lobe of the pituitary gland on the gonadal system has suggested the possibility that these facts might be useful in establishing the diagnosis of pregnancy. Our purpose in this article is to report briefly our experiences with the Aschheim-Zondek test for pregnancy, which one of us (H. W. L.) had the opportunity of observing this spring in the laboratories at the Charite in Berlin. The basis of the test rests on the fact that during pregnancy, as pointed out by Erdheim and Stumme,

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