The IgG Subclass Distribution in 659 Myeloma Sera
- 1 January 1972
- journal article
- Published by Wiley
- Vol. 23 (6) , 546-551
- https://doi.org/10.1159/000466599
Abstract
The IgG subclass of 659 IgG myeloma proteins was determined with subclassspecific antisera in agar precipitation technique. The following distribution was found: IgGl, 80% ; IgG2,10% ; IgG3, 6.4% ; IgG4, 3.6%. In addition, the light chain distribution among myeloma proteins of the subclasses was studied. The K/L ratio of the IgGl proteins was 1.7; IgG2, 2.05; IgG3, 2.2; and IgG4, 3.0. These ratios did not differ significantly. In 9 sera with IgG double M-components, the combination IgGl-IgG4 was found to be predominant.Keywords
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