Synthesis of the carbazole alkaloids carbazomycin A and B and hyellazole

Abstract
The first synthesis of carbazomycins A and B (1) is described; the route involves Diels-Alder reaction of 1-methylpyrano[3,4-b]indol-3-one with ethyl 3-trimethylsilylpropynoate followed by functional group interconversions; the marine alkaloid hyellazole (2) was synthesized by a similar route.

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