THE MERCAPTOLYSIS OF GLUCOSE AND GALACTOSE PENTAACETATES
- 1 December 1951
- journal article
- Published by Canadian Science Publishing in Canadian Journal of Chemistry
- Vol. 29 (12) , 1079-1091
- https://doi.org/10.1139/v51-127
Abstract
The mercaptolysis of the α-and β-pentaacetyl derivatives of glucopyranose and galactopyranose at 0 °C. with zinc chloride catalyst was studied. The β-pentaacetates were rapidly transformed to the corresponding ethyl tetraacetyl-1-thio-β-D-glycosides in excellent yields; however, the α-anomers were highly resistant to the mercaptolytic conditions. The results are interpreted on the basis of a participation by the C2-acetoxy group in the replacements at the lactol carbon atom of the β-pentaacetates with the intermediate formation of a resonance stabilized cyclic carbonium ion.Keywords
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