A Note on the Toxicity and Solvent Properties of Dimethyl Sulphoxide
- 1 September 1963
- journal article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 15 (1) , 688-692
- https://doi.org/10.1111/j.2042-7158.1963.tb12861.x
Abstract
Dimethyl sulphoxide has good solvent properties for a wide range of chemicals, and a low toxicity to mammals. The acute oral LD50 for rats is about 20ml./kg. and for chickens about 12·5 ml./kg. Rats tolerate up to 10 daily doses of 10 ml./kg. weight. Dimethyl sulphoxide is therefore a useful solvent for chemical compounds under toxicological evaluation.Keywords
This publication has 2 references indexed in Scilit:
- Dimethylsulfoxyd als Lösungsmittel für anorganische VerbindungenAngewandte Chemie, 1960
- A Note on Glycerol Formal as a Solvent in Toxicity TestingJournal of Pharmacy and Pharmacology, 1959