Idiopathic Achalasia and Chagasic Megaesophagus

Abstract
The abnormalities of the esophagus and its motility in Chagas' disease are very similar to those in achalasia. But, gastrin levels in Chagas' disease are elevated, and generally the upper gastrointestinal tract, as well as the colon, are hyposensitive to this hormone. In this editorial, I discuss some of the differences in the physiology of the two disorders.

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