Phase III Randomized Trial of Droloxifene and Tamoxifen As First-Line Endocrine Treatment of ER/PgR-Positive Advanced Breast Cancer
- 1 May 2002
- journal article
- clinical trial
- Published by Springer Nature in Breast Cancer Research and Treatment
- Vol. 73 (2) , 161-175
- https://doi.org/10.1023/a:1015229630260
Abstract
Purpose:This trial was designed to demonstrate equivalence between droloxifene 40 mg/d and tamoxifen 20 mg/d as first-line treatment in pre- and post-menopausal women with ER+ and/or PgR+ advanced...Keywords
This publication has 18 references indexed in Scilit:
- Influence of droloxifene on plasma levels of insulin-like growth factor (IGF)-I, pro-IGF-IIE, insulin-like growth factor binding protein (IGFBP)-1 and IGFBP-3 in breast cancer patientsThe Journal of Steroid Biochemistry and Molecular Biology, 1996
- Influence of droloxifene (3-hydroxytamoxifen), 40 mg daily, on plasma gonadotrophins, sex hormone binding globulin and estrogen levels in postmenopausal breast cancer patientsThe Journal of Steroid Biochemistry and Molecular Biology, 1995
- Influence of treatment with the anti-oestrogen 3-hydroxytamoxifen (droloxifene) on plasma sex hormone levels in postmenopausal patients with breast cancerJournal of Endocrinology, 1995
- Influence of tamoxifen on sex hormones, gonadotrophins and sex hormone binding globulin in postmenopausal breast cancer patientsThe Journal of Steroid Biochemistry and Molecular Biology, 1995
- Preclinical data for DroloxifeneCancer Letters, 1994
- Droloxifene, a new antiestrogen: Its role in metastatic breast cancerBreast Cancer Research and Treatment, 1994
- Droloxifene, a new anti-oestrogen in postmenopausal advanced breast cancer: Preliminary results of a double-blind dose-finding phase II trialEuropean Journal Of Cancer, 1992
- Japanese Early Phase II Study of Droloxifene in the Treatment of Advanced Breast Cancer Preliminary Dose-Finding StudyAmerican Journal of Clinical Oncology, 1991
- European Early Phase II Dose-Finding Study of Droloxifene in Advanced Breast CancerAmerican Journal of Clinical Oncology, 1991
- Assessment of response to therapy in advanced breast cancerPublished by Elsevier ,1977