INABILITIES AS AN IMMUNOADJUVANT OF CELL-WALLS OF GROUP-B PEPTIDOGLYCAN TYPES AND THOSE OF ARTHROBACTERS

  • 1 January 1977
    • journal article
    • research article
    • Vol. 20  (1) , 1-4
Abstract
The cell walls from several bacterial species with group B peptidoglycans and those of 2 anthrobacters were inactive or only weakly active as immunoadjuvants in induction of delayed-type hypersensitivity and stimulation of circulating antibody levels to ovalbumin when administered to guinea pigs as a water-in-oil emulsion, in sharp contrast to the group A peptidoglycan adjuvant-active cell walls previously studied. The poor adjuvant activity of these cell walls was discussed in relation to the chemical structures of peptidoglycans. [Cell walls of Microbacterium lacticum, Eubacterium limosum, Corynebacterium poinsettiae, C. insidiosum, C. betae, Arthrobacter sp., A. atrocyaneus and Ampyllariella regularis were used.].

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