Effects of capsaicin pretreatment on the inflammatory response to scalding injury in the rat
- 1 June 1987
- journal article
- Published by Wiley in Acta Physiologica Scandinavica
- Vol. 130 (2) , 345-348
- https://doi.org/10.1111/j.1748-1716.1987.tb08146.x
Abstract
The oedema formation after scalding injury to the rat paw was studied by means of the Evans blue exudation technique. An early and a delayed oedema formation were demonstrated after severe and light scalding, respectively. It was shown that the delayed, but not the early, form was reduced by capsaicin pretreatment, suggesting an involvement of chemosensitive primary sensory neurons in this reaction.Keywords
This publication has 20 references indexed in Scilit:
- Calcitonin gene-related peptide (CGRP) in capsaicin-sensitive substance P-immunoreactive sensory neurons in animals and man: Distribution and release by capsaicinPeptides, 1987
- Multiple tachykinins (neurokinin A, neuropeptide K and substance P) in capsaicin-sensitive sensory neurons in the guinea-pigRegulatory Peptides, 1985
- Comparison of cardiovascular and bronchoconstrictor effects of substance P, substance K and other tachykininsNaunyn-Schmiedebergs Archiv für experimentelle Pathologie und Pharmakologie, 1984
- Immunohistochemical studies on the effect of capsaicin on spinal and medullary peptide and monoamine neurons using antisera to substance P, gastrin/CCK, somatostatin, VIP, enkephalin, neurotensin and 5-hydroxytryptamineJournal of Neurocytology, 1981
- DECREASE OF SUBSTANCE P IN PRIMARY AFFERENT NEURONES AND IMPAIRMENT OF NEUROGENIC PLASMA EXTRAVASATION BY CAPSAICINBritish Journal of Pharmacology, 1980
- Pharmacologically induced selective degeneration of chemosensitive primary sensory neuronesNature, 1977
- Kinin-forming activity and histamine in lymph after tissue injuryThe Journal of Physiology, 1963
- The Nature and the Distribution of Afferent Fibres Provided with the Axon Reflex ArrangementActa Physiologica Scandinavica, 1953
- THE COMPONENT OF THE DORSAL ROOT MEDIATING VASODILATATION AND THE SHERRINGTON CONTRACTUREAmerican Journal of Physiology-Legacy Content, 1930
- On the origin from the spinal cord of the vaso‐dilator fibres of the hind‐limb, and on the nature of these fibres1The Journal of Physiology, 1901