Progression and regression of coronary artery disease

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Abstract
The probability that coronary atherosclerotic lesions will progress increases with their severity and is accentuated further by concomitant hyperlipidaemia. Effective lipid-lowering therapy often arrests or induces regression of such lesions, as has been shown in seven randomized angiographic studies. In three of these trials significant reductions in cardiovascular events were observed, suggestive of plaque stabilization in treated patients.

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