Role of decorin in the antimyeloma effects of osteoblasts
Open Access
- 1 July 2008
- journal article
- Published by American Society of Hematology in Blood
- Vol. 112 (1) , 159-168
- https://doi.org/10.1182/blood-2007-11-124164
Abstract
Building on our previous report that osteoblasts and increased bone formation have a negative impact on myeloma cell growth in a subset of patients,Keywords
This publication has 75 references indexed in Scilit:
- Wnt3a signaling within bone inhibits multiple myeloma bone disease and tumor growthBlood, 2008
- Myeloma-derived Dickkopf-1 disrupts Wnt-regulated osteoprotegerin and RANKL production by osteoblasts: a potential mechanism underlying osteolytic bone lesions in multiple myelomaBlood, 2008
- Increasing Wnt signaling in the bone marrow microenvironment inhibits the development of myeloma bone disease and reduces tumor burden in bone in vivoBlood, 2008
- Antibody-based inhibition of DKK1 suppresses tumor-induced bone resorption and multiple myeloma growth in vivoBlood, 2006
- Decorin Protein Core Inhibits in Vivo Cancer Growth and Metabolism by Hindering Epidermal Growth Factor Receptor Function and Triggering Apoptosis via Caspase-3 ActivationJournal of Biological Chemistry, 2006
- A role for decorin in cutaneous wound healing and angiogenesisWound Repair and Regeneration, 2006
- Decorin prevents metastatic spreading of breast cancerOncogene, 2004
- Phenotype discovery by gene expression profiling: Mapping of biological processes linked to BMP‐2‐mediated osteoblast differentiationJournal of Cellular Biochemistry, 2003
- Transforming growth factor-β and p-21: multiple molecular targets of decorin-mediated suppression of neoplastic growthCell and tissue research, 1999
- Bone marrow angiogenesis and progression in multiple myelomaBritish Journal of Haematology, 1994