Characterization of the secreted antigens of Mycobacterium bovis BCG: comparison of the 46-kilodalton dimeric protein with proteins MPB64 and MPB70
- 1 December 1987
- journal article
- research article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 55 (12) , 3213-3214
- https://doi.org/10.1128/iai.55.12.3213-3214.1987
Abstract
Western blot analysis showed that the 46-kilodalton (kDa) dimeric protein antigen secreted in large amounts by some daughter strains of Mycobacterium bovis BCG corresponded to protein MPB70 present in long-term culture filtrates of the Japanese substrain. The 46/23-kDa antigen is the most abundant protein in supernatant from a 5-day culture but is masked by leaked products in old culture supernatants. No similarities were found between the 46-kDa protein and MPB64, a protein with the same strain distribution, or with the antigen of similar molecular mass recognized by monoclonal antibody SA1.D2D.This publication has 7 references indexed in Scilit:
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- MPB70, A UNIQUE ANTIGEN OF MYCOBACTERIUM-BOVIS BCGPublished by Elsevier ,1984