Concentration of 5-methoxyindoles in the human pineal gland
- 1 March 1982
- journal article
- research article
- Published by Springer Nature in Journal Of Neural Transmission-Parkinsons Disease and Dementia Section
- Vol. 54 (1-2) , 111-116
- https://doi.org/10.1007/bf01249284
Abstract
The pineal gland concentration of the four 5-methoxyindoles: melatonin, 5-methoxytryptamine, 5-methoxytryptophol and 5-methoxyindole-3-acetic acid, were measured by gas chromatography-mass spectrometry. The pineal glands were obtained from 11 subjects 2–3 hourspost mortem. The concentration of 5-methoxytryptophol ranged from 4–93 pmoles/g, 5-methoxyindole-3-acetic acid from 79–560 pmoles/g and melatonin from 24–6860 pmoles/g. 5-methoxytryptamine was present only in trace amounts (0–12 pmoles/g). A variation over time of these compounds was not evident from the data obtained.Keywords
This publication has 6 references indexed in Scilit:
- 5-Methoxyindoles in pineal gland of cow, pig, sheep and ratNaunyn-Schmiedebergs Archiv für experimentelle Pathologie und Pharmakologie, 1981
- 5‐Methoxytryptamine in the human pineal gland: identification and quantitation by mass fragmentographyJournal of Neurochemistry, 1979
- Analysis of 5-methoxytryptamine in brain by gas chromatography mass spectrometryJournal of Mass Spectrometry, 1979
- Melatonin Content of the Human Pineal GlandScience, 1978
- Mass spectra of some specifically deuterated tryptaminesJournal of Mass Spectrometry, 1977