A central neural circuit for experience-independent olfactory and courtship behavior in Drosophila melanogaster
- 11 December 2001
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 98 (26) , 15336-15341
- https://doi.org/10.1073/pnas.011314898
Abstract
We have studied the function of the major central olfactory pathway in fruit flies. Key elements of this pathway, the projection neurons (PNs), connect the antennal lobes with the lateral protocerebrum both directly and indirectly, the latter via the mushroom bodies (MBs). Transgenic expression of tetanus toxin in the majority of PNs and few MB neurons leads to defects in odor detection and male courtship. Considering behavioral data from flies lacking MBs, our results argue that the direct PN-to-lateral protocerebrum pathway is necessary and sufficient to process these experience-independent behaviors. Moreover, the involvement of an olfactory pathway in male courtship suggests a role of volatile attractive female pheromones in Drosophila .Keywords
This publication has 52 references indexed in Scilit:
- Target neuron prespecification in the olfactory map of DrosophilaNature, 2001
- Flexibility in a Single Behavioral Variable of DrosophilaLearning & Memory, 2001
- COURTSHIP INDROSOPHILAAnnual Review of Genetics, 2000
- Functional dissection of the drosophila mushroom bodies by selective feminization ofagenetically defined subcompartmentsNeuron, 1995
- Reverse genetics of Drosophila brain structure and functionProgress in Neurobiology, 1994
- Associative Odor Learning in Drosophila Abolished by Chemical Ablation of Mushroom BodiesScience, 1994
- Chemosensory elements of courtship in normal and mutant, olfaction-deficientDrosophila melanogasterBehavior Genetics, 1986
- The Structural Brain MutantVacuolar medullaofDrosophila melanogasterwith Specific Behavioral Defects and Cell Degeneration in the AdultJournal of Neurogenetics, 1986
- Classical conditioning and retention in normal and mutantDrosophila melanogasterJournal of Comparative Physiology A, 1985
- The role of female movement in the sexual behavior ofDrosophila melanogasterBehavior Genetics, 1982