IDENTIFICATION OF CELLS EXPRESSING T AND P28,33 (IA-LIKE) ANTIGENS IN SECTIONS OF HUMAN LYMPHOID-TISSUE
- 1 January 1980
- journal article
- research article
- Vol. 39 (1) , 66-75
Abstract
A method was developed for identifying human lymphocyte populations in tissue sections using hetero-antisera to T [thymus-derived] cells and to the B [bone marrow-derived] cell associated Ia[immune response associated antigen]-like, p28, 33 polypeptide complex. The differential topographical localization of T and B cells was revealed by simultaneous staining with antibodies tagged with different fluorochromes. This approach also identified a small population of T cells bearing Ia-like antigens. Preliminary studies on lymphomatous tissue suggests this approach will be of value in the study of malignancy and cellular infiltration in disease.This publication has 39 references indexed in Scilit:
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