Site-specific consultation for a chemical mixture
- 1 June 1999
- journal article
- research article
- Published by SAGE Publications in Toxicology and Industrial Health
- Vol. 15 (5) , 470-479
- https://doi.org/10.1177/074823379901500502
Abstract
The Agency for Toxic Substances and Disease Registry (ATSDR) uses the weight of evidence methodology to evaluate interactions of chemical mixtures. In the process, toxicity, toxicokinetics, and toxicodynamics of chemical components of the mixture are carefully examined. Based on the evaluation, predictions are made that can be used in real-life situations at hazardous waste sites. In this paper, health outcomes were evaluated for a mixture of eight compounds that were found at a specific site. These eight chemicals were identified and possibly associated with human exposure. The health assessors could consider similar thought processes when evaluating chemical mixtures at hazardous waste sites.Keywords
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