Stereoselective aldol reactions via enolates of α-acylphosphonate diesters
- 1 January 1990
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 13,p. 922-923
- https://doi.org/10.1039/c39900000922
Abstract
In the reaction between the lithium enolate (2) of diethyl propionylphosphonate (1) and benzaldehyde, the syn-product (3s) is formed with high diastereoselectivity, as a result of structural rigidity caused by Li+ interactions with the phosphoryl oxygen.Keywords
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