Early Diagnosis of Alzheimer's Disease: Clinical and Economic Benefits
- 1 May 2003
- journal article
- review article
- Published by Wiley in Journal of the American Geriatrics Society
- Vol. 51 (5s2) , S281-S288
- https://doi.org/10.1046/j.1532-5415.5153.x
Abstract
An estimated four million individuals in the United States have Alzheimer's disease (AD). This number is expected to more than triple by mid-century. Primary care physicians have a key role in evaluating older patients for early signs of dementia and in initiating treatment that can significantly retard its progression over the maximum period of time. That role and its challenges will inevitably grow along with the expected increase in the population aged 65 and older. The tendency for physicians to dismiss memory complaints as normal aging must be replaced by awareness of the need to assess and possibly intervene. Early intervention is the optimal strategy, not only because the patient's level of function will be preserved for a longer period, but also because community-dwelling patients with AD incur less societal cost than those who require long-term institutional placement. Institutionalization contributes heavily to the annual cost of care for AD in the United States, which is estimated to be 100 billion dollars annually.Keywords
This publication has 51 references indexed in Scilit:
- Is late onset depression a prodrome to dementia?International Journal of Geriatric Psychiatry, 2002
- Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women: Principal Results From the Women's Health Initiative Randomized Controlled TrialJAMA, 2002
- Executive Dysfunction in Geriatric DepressionAmerican Journal of Psychiatry, 2002
- Anxiety, depression and psychosis in vascular dementia: prevalence and associationsJournal of Affective Disorders, 2000
- Is Depression a Risk Factor for Dementia or Cognitive Decline?Gerontology, 2000
- A Controlled Trial of Selegiline, Alpha-Tocopherol, or Both as Treatment for Alzheimer's DiseaseNew England Journal of Medicine, 1997
- Neuropathologic Diagnostic Outcomes From a Cohort of Outpatients With Suspected DementiaThe Journals of Gerontology: Series A, 1996
- Accuracy of Clinical Diagnosis of Alzheimer Disease and Clinical Features of Patients with Non-Alzheimer Disease NeuropathologyAlzheimer Disease & Associated Disorders, 1996
- Predictors of cognitive and functional progression in patients with probable Alzheimer's diseaseNeurology, 1992
- Estimated Prevalence of Alzheimer's Disease in the United StatesThe Milbank Quarterly, 1990