USE OF SULFANILAMIDE AND ITS DERIVATIVES IN OINTMENT FORM

1 September 1942

journal article
research article
Published by American Medical Association (AMA) in Archives of Dermatology and Syphilology

Vol. 46 (3) , 379-385
https://doi.org/10.1001/archderm.1942.01500150045006

Abstract

Sulfanilamide and its derivatives are now being applied in a constantly increasing variety of forms in the treatment of a steadily widening group of dermatoses. In recent months a number of investigators have reported remarkably favorable results from the use of such drugs incorporated in ointment bases. Brunsting¹used a 4 per cent sulfanilamide ointment for impetigo contagiosa. Lain²had success with sulfanilamide in glycerin in the local treatment of various pyodermas. Schnieper,³reporting on 124 patients treated with a 5 per cent sulfathiazole ointment, recommended its use for superficial pyogenic infections. Sams and Capland⁴successfully treated 53 patients (35 with impetigo contagiosa and 12 with ecthyma) with a 5 to 25 per cent sulfathiazole ointment or with sulfathiazole powder. Keeney, Pembroke, Chatard and Ziegler⁵reported curing 8 patients with secondary infection of infantile eczema in seventy-two hours and 10 patients with impetigo contagiosa in

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