Studies on the Natural History of Multiple Sclerosis

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Abstract
ESTIMATES of longevity after onset or diagnosis of multiple sclerosis (MS) have been highly variable, and few have been based on data arising out of a numerically large series collected near onset and followed for a lengthy period. Recent evidence has called into question the common concept that MS is generally progressive and usually fatal within five to 20 years. The US veteran population is an exceptional resource for the study of disease. It comprises an enumerable population, well-indexed at many points of medical interest, and with a potential for long-term follow-up study that is unparalleled in the United States. During World War II a large proportion of the entire population of young men served in the Armed Forces, where medical care was available without regard to prior residence or socioeconomic status. Veterans with service-connected disabilities have been eligible for later medical care under the auspices of the

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