Human odontoblasts contain S‐100 protein‐like immunoreactivity

Publisher Website
Google Scholar
Abstract
S‐100 protein is a group of three closely related isoforms (S‐100ao, S‐100a, and S‐100b). This protein was first described as unique to the nervous system but it has also been identified subsequently in a variety of cell types of neuroectodermal (i. e., melanocytes, glial cells) and non‐neuroectodermal origin (i. e., Langerhans cells, adipocytes, chondrocytes). In the present investigation the presence of S‐100 protein was studied in human odontoblasts using a specific polyclonal antibody directed against S‐100 protein in immunoperoxidase labelling experiments. The S‐100 protein was detected in the cytoplasm of odontoblasts. This result suggests that S‐100 protein can play a role in odontoblast functions.