A Light-Induced Tryptophan-Riboflavin Binding: Biological Implications
- 1 January 1991
- book chapter
- Published by Springer Nature
- Vol. 289, 33-48
- https://doi.org/10.1007/978-1-4899-2626-5_3
Abstract
We review here the covalent photo-binding induced by visible light between the essential amino acid trytophan and the vitamin riboflavin. We discuss the biological implications of this photoadduct in relation to the hepatotoxic and cytotoxic effect associated to parenteral nutrients and to culture media exposed to the action of light, respectively. We also analyze the formation of a photo-binding between riboflavin and the residues of tryptophan present in the proteins of the eye lens, a tissue which is permanently exposed to visible light.Keywords
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