Sensory mechanisms in the upper respiratory tract affect the inhalation of cigarette smoke in man
- 1 July 1986
- journal article
- research article
- Published by Portland Press Ltd. in Clinical Science
- Vol. 71 (1) , 117-119
- https://doi.org/10.1042/cs0710117
Abstract
1. Cigarette puffing parameters (puff volume, puff duration, number of puffs, total smoking time) and inhaled smoke volume (by a radiotracer technique) have been measured in a group of 11 asymptomatic smokers, once after topical anaesthesia of the upper airways and once without anaesthesia. 2. Topical anaesthesia significantly reduced the mean inhaled smoke volume per puff for the group from 41.1 ml to 30.6 ml (P < 0.05) and the total inhaled smoke volume from 575 ml to 528 ml (P = 0.05), but cigarette puffing parameters were unchanged. 3. It is concluded that stimulation of upper airway sensory receptors, probably sensitive to nicotine, may be an important mechanism in determining the amount of cigarette smoke inhaled by smokers.This publication has 2 references indexed in Scilit:
- Reflex control of breathing following inhalation of cigarette smoke in conscious dogsJournal of Applied Physiology, 1983
- Pattern of Breathing during Cigarette SmokingClinical Science, 1981