Enantioselective Addition of Diethylzinc to Aryl Aldehydes Catalyzed by ADPD Imine Catalysts
- 1 September 1998
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1998 (9) , 965-966
- https://doi.org/10.1055/s-1998-1841
Abstract
The use of chiral imines 1-4 prepared from (4S,5S)-(+)-5-amino-2,2-dimethyl-4-phenyl-1,3-dioxane (ADPD) in the enantioselective addition of diethylzinc to aryl aldehydes is reported. Secondary aryl alcohols are obtained up to 85% ee in good yields.Keywords
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