Genetic influences on attention deficit hyperactivity disorder
- 1 March 2000
- journal article
- review article
- Published by Springer Nature in Current Psychiatry Reports
- Vol. 2 (2) , 143-146
- https://doi.org/10.1007/s11920-000-0059-6
Abstract
In this article we review behavioral and molecular genetics studies of attention deficit hyperactivity disorder (ADHD). Family, twin, and adoption studies, along with segregation analyses and molecular genetic studies, all support the hypothesis that both genetic and environmental factors contribute to the etiology of ADHD. Despite this strong evidence for the familial transmission of ADHD, the mode of transmission requires further clarification. In addition, because ADHD appears to be genetically heterogeneous, more work is needed to delineate genetically homogeneous subtypes and describe the range of expression of their underlying genotypes.Keywords
This publication has 57 references indexed in Scilit:
- A haplotype relative risk study of the dopamine D4 receptor (DRD4) exon III repeat polymorphism and attention deficit hyperactivity disorder (ADHD)American Journal of Medical Genetics, 2000
- Haplotype relative risk study of catechol-O-methyltransferase (COMT) and attention deficit hyperactivity disorder (ADHD): Association of the high-enzyme activity val allele with adhd impulsive-hyperactive phenotypeAmerican Journal of Medical Genetics, 1999
- Sex differences in genetic and environmental influences on DSM–III–R attention-deficit/hyperactivity disorder.Journal of Abnormal Psychology, 1999
- Absence of linkage of apparently single gene mediated ADHD with the human syntenic region of the mouse mutantColobomaAmerican Journal of Medical Genetics, 1995
- Segregation analysis of attention deficit hyperactivity disorderPsychiatric Genetics, 1992
- Evidence for a genetic etiology in hyperactivity in childrenBehavior Genetics, 1992
- History of Childhood Behavior Problems in Biological Relatives of Boys With Attention-Deficit Hyperactivity Disorder and Conduct DisorderJournal of Clinical Child Psychology, 1991
- Separation of DSM-III attention deficit disorder and conduct disorder: evidence from a family-genetic study of American child psychiatric patientsPsychological Medicine, 1991
- Hyperactivity and Parental PsychopathologyJournal of Child Psychology and Psychiatry, 1990
- A Twin Study of Hyperactivity—I. An Examination of Hyperactivity Scores and Categories Derived from Rutter Teacher and Parent QuestionnairesJournal of Child Psychology and Psychiatry, 1989