TREATMENT WITH ACYCLOVIR DOES NOT AFFECT OROGENITAL ULCERS IN BEHCÇET'S SYNDROME: A RANDOMIZED DOUBLE-BLIND TRIAL

1 August 1988

journal article
research article
Published by Oxford University Press (OUP) in Rheumatology

Vol. 27 (4) , 300-302
https://doi.org/10.1093/rheumatology/27.4.300

Abstract

Acyclovir is a potent antiviral drug, of proven efficacy in the treatment of herpes simplex virus infection. Since this virus has been implicated in the aetiology of Behcçet's syndrome, the effect of acyclovir on orogenital ulceration in this condition was determined in a randomized, double-blind, placebo-controlled, crossover trial. Eighteen of 22 patients entering the study completed the trial. Treatment with acyclovir failed to alleviate the frequency and severity of orogenital ulceration or other disease features.

Keywords

This publication has 4 references indexed in Scilit:

Acyclovir and Behcet's Disease
Annals of Internal Medicine, 1984
Acyclovir and Behçet's Syndrome
Annals of Internal Medicine, 1984
DETECTION OF RNA COMPLEMENTARY TO HERPES-SIMPLEX VIRUS IN MONONUCLEAR CELLS FROM PATIENTS WITH BEHrET'S SYNDROME AND RECURRENT ORAL ULCERS
The Lancet, 1982
LYMPHOCYTE ABNORMALITIES IN BEHCETS SYNDROME
1980