Global brain dysfunction in an infant with pyridoxine dependency

Abstract
Pyridoxine dependency often presents with intractable seizures in neonates and infants.We describe an infant with pyridoxine-dependent seizures and report the first PET and evoked potential results and EEG and MRI findings. All studies show either diffuse structural or functional abnormality. Our data suggest this coenzyme deficiency causes a generalized disease process. NEUROLOGY 1996;47: 824-826

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