Metrizamide and Radionuclide Cisternography in Communicating Hydrocephalus

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Abstract
Simultaneous 111In-DTPA [diethylenetriaminepentaacetic acid] and metrizamide CT cisternography correlated closely in the qualitative imaging of CSF dynamics in 9 normal patients and in 11 patients thought to have communicating hydrocephalus. CSF clearance of both tracers was similar; significant absorption occurred in the spinal dural sac. Although delayed elevated serum I levels correlated highly with abnormal persistent ventricular penetration (detection at 48 h), these levels cannot be used to predict abnormal ventricular stasis. The pattern of ventricular and cortical sulcus enlargement of the plain CT [computed tomography] scan did not indicate whether the dynamic metrizamide cisternogram would be normal or abnormal.

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