Hypomagnesemia in Neonatal Tetany Associated with Maternal Hyperparathyroidism
- 30 January 1969
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 280 (5) , 260-263
- https://doi.org/10.1056/nejm196901302800508
Abstract
HYPOCALCEMIC tetany has been noted in the offspring of 13 mothers with primary hyperparathyroidism since the initial description by Friderichsen in 1938.1 Transplacental passage of the maternal elevated ionized calcium level leads to suppression of fetal parathyroid function, in addition, the neonate has immature kidneys and parathyroid glands that have limited ability to handle the high phosphate content of cow's milk. In such a neonate, we have noted hypomagnesemia in addition to the expected hypocalcemia.Case ReportA 14-day-old Negro male infant was admitted to the hospital because of intermittent twitching beginning 5 days earlier. On the day of admission . . .Keywords
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