Liquid-chromatographic assay of urinary 5-hydroxy-3-indoleacetic acid, with electrochemical detection.

Open Access

1 June 1980

journal article
Published by Oxford University Press (OUP) in Clinical Chemistry

Vol. 26 (7) , 907-909
https://doi.org/10.1093/clinchem/26.7.907

Abstract

After extraction with two organic solvent mixtures, urinary 5-hydroxy-3-indoleacetic acid can be assayed by "high-performance" liquid chromatography on a reversed-phase column, with electrochemical detection. Compared to the nitrosonaphthol method (J. Biol. Chem. 216: 499, 1955), this method is more specific for detection of patients with carcinoid tumors.

Keywords

CHROMATOGRAPHY
COLUMN
CARCINOID
HYDROXY
CHEM
CHROMATOGRAPHIC
BIOL
REVERSED
INDOLEACETIC
NITROSONAPHTHOL

This publication has 0 references indexed in Scilit: