Modification, sous l’effet de I’alcool, de l’épuration lipidique plasmatique après hyperlipémie induite par le repas gras ou les perfusions d’émulsions lipidiques, chez l’homme

Abstract
The effects of alcohol on plasma lipids removal were studied in 16 control subjects by comparative measurements of turbidity and triglyceridemia. Alcolhol was administered intravenously for 3 h, either after fat meal or 2 h before artificial lipid emulsion infusion. Compared to the control study, alcohol determines a persistant elevation of induced hyperlipemia and was thought to decrease plasma lipids removal. In fact, rats epididymal fat pads lipoprotein lipase activity is decreased after alcohol intraperitoneal administration. Moreover, in man, the fractional removal constant following an intravenous fat tolerance test was slowed down after alcohol infusion. Both results agree with the decreased removal rate of fat emulsion particles and chylomicrons on account of alcohol.

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