Hepatopulmonary Syndrome — A Liver-Induced Lung Vascular Disorder
Top Cited Papers
- 29 May 2008
- journal article
- review article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 358 (22) , 2378-2387
- https://doi.org/10.1056/nejmra0707185
Abstract
The hepatopulmonary syndrome is characterized by defects in oxygenation due to pulmonary abnormalities associated with chronic liver disease. Dyspnea and hypoxemia can be severe and often worsen in the upright position. Gross dilatation of the precapillary and capillary vessels occurs with ventilation–perfusion mismatch. The syndrome usually improves after liver transplantation.Keywords
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