The Irritant Potency ofm-Terphenyl of Different Particle Sizes
- 1 July 1966
- journal article
- research article
- Published by Taylor & Francis in Aihaj Journal
- Vol. 27 (4) , 349-352
- https://doi.org/10.1080/00028896609342840
Abstract
The effect of homogeneous aerosols of m-terphenyl of 0.30, 0.65, 1.0, and 2.0 μ diameter on pulmonary-flow resistance of unanesthetized guinea pigs was studied. At equal mass concentration the irritant potency increased as the particle size decreased and the number of particles increased. A small increase in mass concentration for the smaller particles produced a greater increment in response than occurred when the large particles were used. The results were in agreement with earlier work1 on aerosols of zinc ammonium sulfate.Keywords
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