Pituitary Cytology of Rats with Leydig-Cell Tumors Induced by Low-Level Testicular Irradiation

Abstract
The pituitary gland cytology of rats subjected to local testicular irradiation was studied. Although rats treated with 500 R X-rays had a high incidence of testicular atrophy, interstitial-cell hyperplasia, and Leydig-cell tumors, increased incidences of gonadotropic hyperplasia and adenomas were not found. We could find no statistical relationship between degenerative, hyperplastic, and neoplastic lesions of the testes and pituitary gonadotropic hyperplasia and adenomas.

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