Synthesis and spectroscopic studies of the pyrimidine-2(1H)thione derivatives
- 15 October 1979
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Chemistry
- Vol. 57 (20) , 2734-2742
- https://doi.org/10.1139/v79-442
Abstract
1,3-Diaryl-2-propen-1-ones 1 reacted with thiourea in the presence of sodium ethoxide to give 4,6-diaryl-3,4-dihydropyrimidine-2(1H)thiones 5 which upon dehydrogenation with 3 mol of ethanolic sodium ethoxide yielded the corresponding 4,6-diarylpyrimidine-2(1H)thiones 9. The N-acetyl derivatives of the former thiones were prepared. Infrared, nuclear magnetic resonance, and ultraviolet spectral data of the above compounds were tabulated and discussed.This publication has 0 references indexed in Scilit: