Efficient synthesis of 2-hydroxycyclobutanone derivatives; application to the synthesis of 1,4-diketones and cyclopentenones
- 1 January 1977
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 16,p. 573-574
- https://doi.org/10.1039/c39770000573
Abstract
Treatment of 4,4-(trimethylenedithio)butanal meso-1,2-diphenylethylene acetal (3) with butyl-lithium gave a high yield of 2,2-(trimethylenedithio)cyclobutanol (8), which was transformed into 2-tetrahydropyran-2-yl-oxycyclobutanone (11), a potential intermediate for the synthesis of 1,4-diketones and cyclopentenones.Keywords
This publication has 0 references indexed in Scilit: