Current and Potential Uses of Imiquimod
- 1 September 2005
- journal article
- review article
- Published by Southern Medical Association in Southern Medical Journal
- Vol. 98 (9) , 913-919
- https://doi.org/10.1097/01.smj.0000176712.01491.98
Abstract
Imiquimod, an imidazoquinoline amine, is an immune response modifier first FDA-approved for the treatment of external genital and perianal warts in 1997. Since its appearance on the market, its antiviral and antitumor properties have been used in the treatment of a variety of dermatologic conditions. In this review article, the basic mechanism of action of imiquimod, current FDA-approved and...Keywords
This publication has 35 references indexed in Scilit:
- Low Incidence of New Actinic Keratoses After Topical 5% Imiquimod Cream Treatment: A Long-term Follow-up StudyArchives of Dermatology, 2004
- Imiquimod 5% cream for the treatment of actinic keratosis: results from two phase III, randomized, double-blind, parallel group, vehicle-controlled trialsJournal of the American Academy of Dermatology, 2004
- Imiquimod 5% cream for the treatment of superficial basal cell carcinoma: results from two phase III, randomized, vehicle-controlled studiesJournal of the American Academy of Dermatology, 2004
- Topically Applied Imiquimod Inhibits Vascular Tumor Growth In VivoJournal of Investigative Dermatology, 2003
- A Randomized, Double-blind, Vehicle-Controlled Study to Assess 5% Imiquimod Cream for the Treatment of Multiple Actinic KeratosesArchives of Dermatology, 2002
- Topical 5% imiquimod for the therapy of actinic cheilitisJournal of the American Academy of Dermatology, 2002
- Cycle therapy of actinic keratoses of the face and scalp with 5% topical imiquimod cream: An open-label trialJournal of the American Academy of Dermatology, 2002
- Small anti-viral compounds activate immune cells via the TLR7 MyD88–dependent signaling pathwayNature Immunology, 2002
- Review Article Imiquimod applied topically: a novel immune response modifier and new class of drugInternational Journal of Immunopharmacology, 1999
- Self-administered Topical 5% Imiquimod Cream for External Anogenital WartsArchives of Dermatology, 1998