Acute Mountain Sickness

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Abstract
THE majority of persons who ascend rapidly to terrestrial elevations higher than approximately 2500 m (8200 ft) undergo an unpleasant period of acclimatization. During this time, they have a variety of symptoms, the most prominent of which are headache, nausea, vomiting, and insomnia, that are collectively referred to as acute mountain sickness.1 2 3 This paper reviews current concepts of the pathogenesis and treatment of this disorder. Factors that influence susceptibility to this condition will be discussed. Acute mountain sickness is part of a continuum of diseases related to ascension to high altitudes4 that includes the infrequent life-threatening conditions high-altitude pulmonary edema . . .